: being the preferred, standard, or first choice
first-line treatment of tuberculosis
compare second-line

Examples of first-line in a Sentence

surgery is usually not considered a first-line treatment for this type of cancer
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Until now, levodopa has been the standard first-line treatment for Parkinson’s patients. Melissa Rudy, FOXNews.com, 18 Apr. 2025 These agents are considered first-line agents10 to reduce fluid volume; however, that depends on individual factors. Jessica Swirble, Verywell Health, 17 Apr. 2025 Last, for frontline and first-line leadership talent, your best source is referrals from your existing A-player employees. Verne Harnish, Forbes.com, 16 Apr. 2025 Stimulant drugs like methylphenidate (Ritalin, Concerta) that are designed to improve attention are first-line treatments for ADHD. New Atlas, 14 Apr. 2025 See All Example Sentences for first-line

Word History

First Known Use

1919, in the meaning defined above

Time Traveler
The first known use of first-line was in 1919

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Cite this Entry

“First-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/first-line. Accessed 29 Apr. 2025.

Medical Definition

first-line

adjective
: being the preferred, standard, or first choice
first-line treatment of advanced breast cancer
compare second-line
Last Updated: - Updated example sentences
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