Definition of first-linenext
as in selected
singled out from a number or group as more to one's liking surgery is usually not considered a first-line treatment for this type of cancer

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Antonyms & Near Antonyms

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of first-line The drug is being positioned as a first-line treatment option. Justin Zacks, CNBC, 4 June 2026 Right now, chemotherapy is still recommended as a first-line treatment for patients with advanced pancreatic cancer. Erika Edwards, NBC news, 31 May 2026 But not everyone responds to this line of treatment, and those who fail first-line therapies are often left without next steps. Freda Kreier, Hartford Courant, 30 May 2026 Richman, the Citizen Oversight Board member, does not believe first-line supervisors are equipped to thoroughly review misconduct allegations and make informed decisions on what warrants further review. Shelly Bradbury, Denver Post, 29 May 2026 See All Example Sentences for first-line
Recent Examples of Synonyms for first-line
Adjective
  • Some cool features include a kill switch that automatically disconnects you from the internet if the VPN connection fails, as well as split tunneling that allows selected apps to use the VPN connection while others transmit data in clear text.
    K. Thor Jensen, PC Magazine, 25 June 2026
  • These pre-selected fighter pilots and their families moved into their apartments during the summer of 1960 after residing at the Frunze Central Airfield in Moscow.
    Jeff Spry, Space.com, 27 May 2026
Adjective
  • For a more exclusive access, sign up for the chef’s experience, which includes visits to the Sonoma Farmers Market, Vella Cheese Company, and The Farmer’s Patch to hand-select ingredients for your dinner.
    Kaila Yu, Forbes.com, 30 June 2026
  • But history happens to all of us, not just a select few.
    Theater Critic, Los Angeles Times, 29 June 2026
Adjective
  • Right on time, a loyal customer walks in and heads straight to his favorite spot.
    Alana Al-Hatlani, Southern Living, 1 July 2026
  • Check out more of my favorite beauty products from this year below.
    Tamim Alnuweiri, InStyle, 1 July 2026
Adjective
  • Success rarely arrives on our preferred timeline.
    Melissa Dawn Simkins, Fortune, 22 June 2026
  • Later this week, the government releases its May personal consumption expenditures price index, the preferred inflation gauge of the Federal Reserve.
    ABC News, ABC News, 22 June 2026
Adjective
  • Each time, job losses were met with commissions and task forces, issuing job predictions and calls for government to plan and spur jobs in favored sectors, such as clean energy, healthcare and social services.
    Michael Bernick, Forbes.com, 23 June 2026
  • Of that $35 million, nearly $10 million in Medicaid settlement money was funneled through the first lady’s favored charity, Hope Florida, to anti-amendment efforts.
    Sun Sentinel Editorial Board, Sun Sentinel, 6 June 2026

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Cite this Entry

“First-line.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/first-line. Accessed 5 Jul. 2026.

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