as in selected
singled out from a number or group as more to one's liking
surgery is usually not considered a first-line treatment for this type of cancer
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Recent Examples of first-line
Even the current first-line oral treatment, fexinidazole, must be taken for 10 days and comes with severe side effects such as nausea, vomiting and heart-rhythm disturbances.
—
Fran Kritz, NPR, 16 Mar. 2026
That may help researchers identify which patient populations should get immunotherapy as a first-line treatment.
—Kerry Breen, CBS News, 14 Mar. 2026
The American College of Physicians recommends CBT-I as the first-line treatment for chronic insomnia.
—Allison Palmer
march 4, Charlotte Observer, 4 Mar. 2026
Now, in a new paper in the journal Cell Press Blue, researchers report that if the tissue’s first-line defenses fail, then what could have been a mild infection spirals out of control.
—Veronique Greenwood, Time, 27 Feb. 2026
See All Example Sentences for first-line
Fran Kritz, NPR, 16 Mar. 2026
That may help researchers identify which patient populations should get immunotherapy as a first-line treatment.
—Kerry Breen, CBS News, 14 Mar. 2026
The American College of Physicians recommends CBT-I as the first-line treatment for chronic insomnia.
—Allison Palmer
march 4, Charlotte Observer, 4 Mar. 2026
Now, in a new paper in the journal Cell Press Blue, researchers report that if the tissue’s first-line defenses fail, then what could have been a mild infection spirals out of control.
—Veronique Greenwood, Time, 27 Feb. 2026
See All Example Sentences for first-line
Recent Examples of Synonyms for first-line
Adjective
-
The gist, however, seems to be that extra-terrestrials make contact with a selected few, before promising to go public to the entire world — good luck dealing with the ramifications of that one, human race!—
Richard Edwards,
Space.com,
31 Dec. 2025
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The selected cohort—Diamond Batiste, Ciara Boniface, Jeremy Hsing, Alejandra López and Brittany Alexia Young—were chosen from nearly 1,000 submissions, placing them at the forefront of a new chapter in cinematic storytelling.—
Okla Jones,
Essence,
23 Oct. 2025
Adjective
-
Each ticket costs $5, and players may pick six numbers from two separate pools of numbers — five different numbers from 1 to 70 (the white balls) and one number from 1 to 24 (the gold Mega Ball) — or select Easy Pick/Quick Pick.—
Fernando Cervantes Jr,
USA Today,
4 Apr. 2026
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In past labor actions, the district has continued providing meals at select sites.—
Teresa Liu,
Daily News,
4 Apr. 2026
Adjective
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The teenager is looking to follow in his father's footsteps, and counts Black Label Society's Zakk Wylde as his favorite guitarist.—
Ralphie Aversa,
USA Today,
2 Apr. 2026
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If possible, set aside some time today to journal, listen to your favorite music, or just take a nap!—
Tarot.com,
Sun Sentinel,
1 Apr. 2026
Adjective
-
Fifty-three percent of respondents at the Conservative Political Action Conference last weekend said Vance was their preferred candidate in the 2028 Republican primary.—
Gabe Kaminsky,
CBS News,
31 Mar. 2026
-
Why Musk is pivoting Tesla watch now Choose CNBC as your preferred source on Google and never miss a moment from the most trusted name in business news.—
Lora Kolodny,
CNBC,
30 Mar. 2026
Adjective
-
Periods of technological transformation often coincide with capital over-concentration, valuation compression outside the favored theme, and eventual normalization.—
Matt Witheiler,
Fortune,
4 Apr. 2026
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The Washington Consensus was traditionally wary of developing countries picking winners and losers, erecting trade barriers and subsidizing favored industries.—
Editorial Board,
Washington Post,
24 Mar. 2026
Cite this Entry
“First-line.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/first-line. Accessed 5 Apr. 2026.
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