metastasize

verb

me·​tas·​ta·​size mə-ˈta-stə-ˌsīz How to pronounce metastasize (audio)
metastasized; metastasizing

intransitive verb

: to spread or grow by or as if by metastasis
… died of lung cancer which had metastasized throughout his body.G. P. Elliott

Examples of metastasize in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
On the left, that dislike has metastasized into an all-out fury, which is manifesting itself in all kinds of intolerable ways. Chris Roemer, Baltimore Sun, 7 Feb. 2026 Experts fear the security crisis could soon metastasize beyond Nigeria’s borders. semafor.com, 6 Feb. 2026 Civil society, educators, law enforcement, technology platforms and international partners must work together to prevent hatred from metastasizing into violence. Brian Siegal, Sun Sentinel, 22 Jan. 2026 Debra was in remission for 15 years after a bone marrow transplant, chemotherapy, breast surgery and radiation sessions, though her cancer eventually returned and metastasized. Jordana Comiter, PEOPLE, 21 Jan. 2026 See All Example Sentences for metastasize

Word History

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of metastasize was in 1907

Browse Nearby Words

Cite this Entry

“Metastasize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metastasize. Accessed 14 Feb. 2026.

Kids Definition

metastasize

verb
me·​tas·​ta·​size mə-ˈtas-tə-ˌsīz How to pronounce metastasize (audio)
: to spread or grow by or as if by metastasis

Medical Definition

metastasize

intransitive verb
me·​tas·​ta·​size
variants also British metastasise
metastasized also British metastasised; metastasizing also British metastasising
: to spread by metastasis
… all ten were primary brain cancers; that is, they had originated in the brain, and not metastasized there from elsewhere in the body.Paul Brodeur, The New Yorker
metastasization noun
also British metastasisation
Last Updated: - Updated example sentences
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