serotonin

noun

se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio)
ˌser-
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

Examples of serotonin in a Sentence

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Mood changes: High protein with insufficient carbohydrates may impact serotonin (a feel-good hormone) levels, affecting mood and energy levels.17 Great Food Sources Protein is found in almost every food (including broccoli), but some foods are better sources than others. Lauren Panoff, Mph, Rd, Verywell Health, 18 Apr. 2025 There's no surer cure for the blues than a shot of serotonin straight to the heart in the form of one of the best rom-coms of all time. Elizabeth Logan, Glamour, 14 Apr. 2025 Accordingly, there are some tense moments, but mostly A League of Their Own concerns lusting after a young Tom Hanks and watching Madonna and Rosie O’Donnell run around in period softball costumes—a.k.a. instant serotonin. Emma Specter, Vogue, 6 Apr. 2025 Exercise can boost levels of the hormones serotonin and dopamine, both of which can improve your overall mood and feelings of well-being. Wendy Wisner, Health, 31 Mar. 2025 See All Example Sentences for serotonin

Word History

Etymology

sero- + ton(ic) entry 2 or tone entry 1 + -in entry 1, probably after angiotonin, earlier name for angiotensin — more at angiotensin

Note: Term introduced by Maurice M. Rapport, Arda Alden Green and Irvine H. Page in "Crystalline serotonin," Science, vol. 108, Issue 2804 (September 24, 1948), pp. 329-330: "The general behavior of the crystalline substance is suggestive of its homogeneity. We would like provisionally to name it serotonin, which indicates that its source is serum and its activity is one of causing constriction."

First Known Use

1948, in the meaning defined above

Time Traveler
The first known use of serotonin was in 1948

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Cite this Entry

“Serotonin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/serotonin. Accessed 30 Apr. 2025.

Medical Definition

serotonin

noun
se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio) ˌser- How to pronounce serotonin (audio)
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

called also 5-HT, 5-hydroxytryptamine

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