as in ordeal
a negative event or circumstance that is common to a particular setting or situation and is usually beyond one's control
The vicissitudes of medical school proved too much for the anxious student.
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Recent Examples of vicissitude
People who pay attention to the vicissitudes of Tesla CEO Elon Musk know that the man is not always serious on Twitter.
—
Aarian Marshall, Wired, 10 May 2020
The vicissitudes of history always challenge us in new and often confounding ways; that’s in the nature of things.
—Jon Meacham, New York Times, 24 Mar. 2020
All of the biggest corporate mergers, the deals that determine the vicissitudes of our global markets, happen within their walls.
—Rachel Epstein, Marie Claire, 30 Mar. 2020
Sport is usually a constant -- a field, court, track or course that is resistant to the vicissitudes of the world around us.
—George Ramsay, CNN, 12 Mar. 2020
See All Example Sentences for vicissitude
Aarian Marshall, Wired, 10 May 2020
The vicissitudes of history always challenge us in new and often confounding ways; that’s in the nature of things.
—Jon Meacham, New York Times, 24 Mar. 2020
All of the biggest corporate mergers, the deals that determine the vicissitudes of our global markets, happen within their walls.
—Rachel Epstein, Marie Claire, 30 Mar. 2020
Sport is usually a constant -- a field, court, track or course that is resistant to the vicissitudes of the world around us.
—George Ramsay, CNN, 12 Mar. 2020
See All Example Sentences for vicissitude
Recent Examples of Synonyms for vicissitude
Noun
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One victim, the father of a crypto millionaire, was allegedly held for days in a house south of Paris — and reportedly had a finger severed during the ordeal.—
MacKenzie Sigalos,
CNBC,
7 June 2025
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Nearly two hours later, someone called 911 about diesel in the Harbor East marina, and by 2 p.m., officials began responding to the ordeal.—
Saleen Martin,
USA Today,
6 June 2025
Noun
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Neither team survived the regional and super regional gauntlet to be one of the last eight teams standing.—
Brady Oltmans,
Los Angeles Times,
12 June 2025
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As the story unfolds, Musashi wants to carve his own path and earn his stripes as a samurai without relying on the soul-absorbing Oni gauntlet strapped to his arm.—
Zackery Cuevas,
PC Magazine,
11 June 2025
Noun
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Escobar had the misfortune of stepping into the shadow of the past season with skeletons in her closet.—
Larisha Paul,
Rolling Stone,
5 June 2025
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Plenty of other contenders faced similar misfortune.—
Steve Megargee,
Chicago Tribune,
31 May 2025
Noun
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But whereas the first generation of Chinese entrepreneurs grew up poor and were happy to wring a livelihood from cheap imitations, today’s tech graduates were spared the privations of their parents and yearn for something more meaningful.—
Charlie Campbell,
Time,
29 May 2025
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For another thing, squeezing the Russian economy is unlikely to produce sufficient privation to create meaningful political pressure against Putin.—
Barry R. Posen,
Foreign Affairs,
8 July 2022
Cite this Entry
“Vicissitude.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/vicissitude. Accessed 19 Jun. 2025.
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