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Synonym Chooser

How does the adjective refractory differ from other similar words?

Some common synonyms of refractory are headstrong, intractable, recalcitrant, ungovernable, unruly, and willful. While all these words mean "not submissive to government or control," refractory stresses resistance to attempts to manage or to mold.

special schools for refractory children

When can headstrong be used instead of refractory?

The words headstrong and refractory can be used in similar contexts, but headstrong suggests self-will impatient of restraint, advice, or suggestion.

a headstrong young cavalry officer

Where would intractable be a reasonable alternative to refractory?

While in some cases nearly identical to refractory, intractable suggests stubborn resistance to guidance or control.

intractable opponents of the hazardous-waste dump

When would recalcitrant be a good substitute for refractory?

Although the words recalcitrant and refractory have much in common, recalcitrant suggests determined resistance to or defiance of authority.

acts of sabotage by a recalcitrant populace

In what contexts can ungovernable take the place of refractory?

The meanings of ungovernable and refractory largely overlap; however, ungovernable implies either an escape from control or guidance or a state of being unsubdued and incapable of controlling oneself or being controlled by others.

ungovernable rage

When is unruly a more appropriate choice than refractory?

The synonyms unruly and refractory are sometimes interchangeable, but unruly implies lack of discipline or incapacity for discipline and often connotes waywardness or turbulence of behavior.

unruly children

When could willful be used to replace refractory?

The words willful and refractory are synonyms, but do differ in nuance. Specifically, willful implies an obstinate determination to have one's own way.

a willful disregard for the rights of others

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of refractory This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA. Kansas City Star, 13 May 2024 Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study. Meghana Keshavan, STAT, 15 Apr. 2024 All of the children had rare, relapsed or refractory cancers and were running out of treatment options. Michelle Marchante, Miami Herald, 11 Apr. 2024 Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients. Damian Garde, STAT, 13 Dec. 2023 See All Example Sentences for refractory
Recent Examples of Synonyms for refractory
Adjective
  • Aquarius: Justin Suarez Socially conscious and true fashionista, Justin’s creativity and free spirit very much align with Aquarius’ rebellious nature and sparkling individuality.
    Valerie Mesa, People.com, 14 Apr. 2025
  • It’s been 150 years since the Impressionists shocked Paris with their rebellious Société Anonyme show.
    Nazanin Lankarani, New York Times, 13 Apr. 2025
Adjective
  • Why Communication Training Often Fails To Stick Some people are very stubborn and stick to their communication style, even when confronted.
    Dr. Diane Hamilton, Forbes.com, 23 Apr. 2025
  • The most glaring of those misses came against Arsenal in October, with Bournemouth trying to break down a stubborn defence following William Saliba’s dismissal.
    Anantaajith Raghuraman, New York Times, 23 Apr. 2025
Adjective
  • Plutarch, future Head Gamemaker of the 75th Hunger Games and commander of the rebel forces, is a young Capitol cameraman in this timeline who is tasked with documenting the tributes of District 12.
    EW.com, EW.com, 25 Apr. 2025
  • The civil war in Sudan, between the government’s SAF and the rebel Rapid Support Forces (RSF), has just passed its grisly second anniversary.
    Paul Tilsley, FOXNews.com, 24 Apr. 2025
Adjective
  • New young friends were happy to de-bollix our recalcitrant computer.
    Murr Brewster, Christian Science Monitor, 16 Apr. 2025
  • For recalcitrant teams, Scherzer would also remove the runner who automatically starts each inning after the ninth in scoring position on second base, creating a significant handicap.
    Bruce Schoenfeld Robert Fass Tanya Pérez Brian St. Pierre, New York Times, 26 Mar. 2025
Adjective
  • Hegseth, a veteran and former Fox News host, was defiant in remarks to reporters earlier Monday.
    Brett Samuels, The Hill, 21 Apr. 2025
  • But when asked about the lack of norms and decorum in the current political climate and whether Democrats need to play on the same level, Himes was defiant.
    Lisa Hagen, Hartford Courant, 19 Apr. 2025
Adjective
  • But where others saw an intractable problem, Jean-François Archambault saw an opportunity.
    Afdhel Aziz, Forbes.com, 15 Apr. 2025
  • But since the end of the Cold War, there have been many more wars in which early successes faltered, lost momentum, or didn’t quite achieve enough, transforming the conflicts into something far more intractable.
    Lawrence D. Freedman, Foreign Affairs, 14 Apr. 2025
Adjective
  • At least, as much as possible in an inherently uncontrollable industry.
    Lizz Schumer, People.com, 24 Apr. 2025
  • The sloppy security breaches, the embarrassing headlines, the uncontrollable infighting and undermining, the lack of accountability — this all belongs to Hegseth.
    S.E. Cupp, New York Daily News, 23 Apr. 2025
Adjective
  • These expenses, which lead to unmanageable debt, can include medical emergencies, natural disasters, and car repairs.
    Víctor Rosario, Sacbee.com, 28 Mar. 2025
  • The federal government, with its millions of employees, has ballooned into an unmanageable monstrosity, consuming trillions of taxpayer dollars while failing at even the most basic functions.
    Paul Du Quenoy, MSNBC Newsweek, 26 Mar. 2025

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Cite this Entry

“Refractory.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractory. Accessed 30 Apr. 2025.

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